SL 220K 723 W. Michigan Street Indianapolis, IN 46202
Education
Ph.D. Bioengineering, Clemson University, 2007
Professional Experience
Assistant Professor, Department of Biomedical Engineering, Indiana University-Purdue University Indianapolis, 8/2010 - present
Postdoctoral Associate, Department of Chemical & Biological Engineering, Howard Hughes Medical Institute & University of Colorado at Boulder, 9/2007 - 7/2010
Graduate Research Assistant, Department of Bioengineering, Clemson University, 8/2004 - 8/2007
Abraham M. Max Distinguished Professor Award, Purdue School of Engineering & Technology, IUPUI. 2017
Honorary Scientist and Advisor on Agricultural Science & Technology, the Rural Development Administration of the Republic of Korea, 7/2017
US Frontiers of Engineering Symposium Invitee, National Academy of Engineering, 9/2015
Faculty Early Career Development (CAREER) Award, National Science Foundation, 7/2015
Purdue Summer Faculty Research Grant, Purdue Research Foundation, 7/2014
Young Investigator Award, Frontiers in Bioengineering Workshop, Georgia Institute of Technology, 2/2013
American Institute of Chemists Postdoctoral Award, University of Colorado , 7/2010
Outstanding Graduate Research Assistant Award, Graduate School & Clemson University Research Foundation, 7/2007
Outstanding Graduate Researcher Award, College of Engineering & Science,Clemson University , 7/2007
Selected Publications
Nguyen HD, Liu HY, Hudson BN, Lin CC*. Enzymatic crosslinking of dynamic thiol-norbornene click hydrogels. ACS Biomaterials Science & Engineering 2019 (5) 1247-1256
Arkenberg MR, Moore D, and Lin CC*. Dynamic control of hydrogel crosslinking via sortase-mediated reversible transpeptidation. Acta Biomaterialia 2019 (83) 83-95
Liu HY, Nguyen H, Lin CC*. Dynamic PEG-peptide hydrogels via visible light and FMN-induced tyrosine dimerization.Advanced Healthcare Materials 2018 (7) 1800954
Lin CC*, Korc M. Designer hydrogels: Shedding light on the physical chemistry of the pancreatic cancer microenvironment. Cancer Letters 2018 (436) 22-27
Liu HY, Korc M, and Lin CC*. Biomimetic and enzyme-responsive dynamic hydrogels for studying cell-matrix interactions in pancreatic ductal adenocarcinoma. Biomaterials 2018 (160) 24-36
Arkenberg MR and Lin CC*. Orthogonal enzymatic reactions for rapid crosslinking and dynamic tuning of PEG-peptide hydrogels. Biomaterials Science 2017 (5) 2231-2240
Liu HY, Greene T, Lin TY, Dawes CS, Korc M, and Lin CC*. Enzyme-mediated stiffening hydrogels for probing activation of pancreatic stellate cells. Acta Biomaterialia 2017 (48) 258-269
Shih H, Greene T, Korc M, and Lin CC*. Modular and adaptable tumor niche prepared from visible light-initiated thiol-norbornene photopolymerization. Biomacromolecules 2016 (17) 3872-3882
Shih H and Lin CC*. Tuning stiffness of cell-laden hydrogels via host-guest interaction. Journal of Materials Chemistry B 2016 (4)4969-4974
Ki CS, Lin TY, Korc M, and Lin CC*. Thiol-ene hydrogels as desmoplasia-mimetic matrices for modeling pancreatic cancer cell growth, invasion, and drug resistance. Biomaterials 2014(35) 9668-9677
Lin TY, Ki CS, and Lin CC*. Manipulating hepatocellular carcinoma cell fate in orthogonally cross-linked hydrogels.Biomaterials 2014(35) 6898-6906
Munoz Z, Shih H, and Lin CC*.Gelatin hydrogels formed by orthogonal thiol-norbornene photochemistry for cell encapsulation. Biomaterials Science 2014(2) 1063-1072
Hao Y, Shih H, Munoz Z, Kemp A, Lin CC*. Visible light cured thiol-vinyl hydrogels with tunable degradation for 3D cell culture. Acta Biomaterialia 2014(10) 104-114
Raza A, Ki CS, and Lin CC*. The influence of matrix properties on growth and morphogenesis of pancreatic ductal epithelial cell in 3D. Biomaterials 2013(34) 5117-5127
Shih H and Lin CC*. Visible light-mediated thiol-ene hydrogelation using eosin-Y as the only photoinitiator.Macromolecular Rapid Communications 2013(34) 269-273
Shih H and Lin CC*. Crosslinking and degradation of step-growth hydrogels formed by thiol-ene photo-click chemistry.Biomacromolecules 2012(13) 2003-2012
Lin CC*, Raza A, Shih H. PEG hydrogels formed by thiol-ene photo-click chemistry and their effect on the formation and recovery of insulin-secreting cell spheroids. Biomaterials 2011(32) 9685-9695
Our research focuses on designing multifunctional polymeric biomaterials, including hydrogels, nanoparticles, and cell surface coatings, for releasing therapeutically relevant agents and for delivering adult, stem, and progenitor cells for tissue engineering and regenerative medicine applications.
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